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Module 3: The Body's Response to Injury

Segment 7: Tissue Oxygen Utilization

References labeled PEDS contain a pediatric element or primary focus.

Topic: Tissue oxygen utilization

  • Bakker J. Lactate is THE target for early resuscitation in sepsis. Rev Bras Ter Intensiva. 2017;29(2):124-127. doi: 10.5935/0103-507X.20170021 https://pubmed.ncbi.nlm.nih.gov/28977252/.
  • Brux H, Vom Dahl J, Haake H. Lactate level and clearance as predictors of neurologic outcome after cardiopulmonary resuscitation. Am J Crit Care. 2023;32(2):81-91. doi: 10.4037/ajcc2023991 https://pubmed.ncbi.nlm.nih.gov/36854915/.
  • Callaway DW, Shapiro NI, Donnino MW, et al. Serum lactate and base deficit as predictors of mortality in normotensive elderly blunt trauma patients. J Trauma. 2009;66(4):1040-4. doi: 10.1097/TA.0b013e3181895e9e https://pubmed.ncbi.nlm.nih.gov/19359912/.
  • Chebl RB, Khuri CE, Shami A, et al. Serum lactate is an independent predictor of hospital mortality in critically ill patients in the emergency department: a retrospective study. Scand J Trauma Resusc Emerg Med. 2017;25(69) doi: 10.55460/XB1Z-3BJU https://pubmed.ncbi.nlm.nih.gov/28705203/.
  • Ducrocq N, Kimmoun A, Levy B. Lactate or ScvO2 as an endpoint in resuscitation of shock states? Minerva Anestesiol. 2013;79(9):1049-58. doi:  https://pubmed.ncbi.nlm.nih.gov/24042154/.
  • Wardi G, Brice J, Correia M, et al. Demystifying lactate in the emergency department. Ann Emerg Med. 2020;75(2):287-298. doi: 10.1016/j.annemergmed.2019.06.027 https://pubmed.ncbi.nlm.nih.gov/31474479/.
  • White KM. Using continuous SVO2 to assess oxygen supply/demand balance in the critically ill patient. AACN Adv Crit Care. 1993;4(1):134-47. doi:  https://pubmed.ncbi.nlm.nih.gov/8452736/.
  • Zhao X, Xiao H, Cai J, et al. Double standards: why is pulse oximetry standard care, whereas tissue oximetry is not? Curr Opin Anaesthesiol. 2020;33(5):619-625. doi: 10.1097/aco.0000000000000910 https://pubmed.ncbi.nlm.nih.gov/32826624/.